AstraZeneca fined for anti-psychotic drug

Anglo-Swedish pharmaceutical firm AstraZeneca has agreed to pay a $510 million fine to settle a case alleging that it illegally marketed an anti-psychotic drug, the US justice department has confirmed.

The firm's US division agreed to the fine for marketing the the anti-psychotic drug Seroquel for so-called "off-label" uses not included in the drug's approved product label, the Justice Department said.

US authorities contended that AstraZeneca illegally marketed Seroquel for uses never approved by the Food and Drug Administration (FDA) such as aggression, Alzheimer's disease, anger management, anxiety, attention deficit hyperactivity disorder, bipolar maintenance, dementia, depression, mood disorder, post-traumatic stress disorder, and sleeplessness.

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Getting Serious

It's time to get serious again. Those of you who struggle with weight and depression know what I mean. One day you wake up and you know you have the energy to take a shot at getting your body and mood under control. And you feel confident that this time, you will be triumphant.

I woke up feeling that way this morning. I actually got out and walked, not just lay in bed or puttered around the house thinking I'd like to. Didn't go far, just around our complex. But it was a start, and part of the reason we fail so often is we try to take too big a bite . . . try to change too much too fast.

From Calories Per Hour:

Unless you are excited to be following a very specific diet and exercise plan, do not try and change too much too fast. If you have been eating poorly and not exercising, both your body and your mind will have a lot of adjusting to do.

All the sugar and fat were actually quite enjoyable, and sitting on the couch didn't feel too bad, either. If you try and change everything too quickly the odds are greater that you will feel bad, get discouraged, and give up. So be patient.

A time will come when a healthy snack will taste as good as the junk food you felt bad about eating, and you will look forward to your regular exercise.

This is what I do. I jump in and try to change all the bad habits at once . . overcome enui that has ruled my life for months or years. But I often fail quickly because, honestly, I'm a creature of habit and the habits I have developed have stood me in good stead in surviving depression and mania. So trying to change everything at once often leaves me feeling lost . . .adrift without any anchor.

With that in mind, I've actually already started. Over a year ago I signed up for a Twitter based app called Your Flowing Data. I didn't use it very much for a year. Then a couple of weeks ago I felt my spring surge building and started recording some things. I have successfully kept track of my getting up and going to bed, blood pressure twice a day and my weight daily for over a week. As I progress I will add other things . . .not only what I eat, but vitamins and meds. This may seem onerous, but I can do most of this via my Blackberry Twitter login.

So I will be keeping a food log, something almost every weight loss expert agrees is the one thing that will guarantee success. If you are like me you have done this time and again. I've even designed my own food log, really cute little pocket sized number. And sometimes I could manage to keep tracks for a month . .before I lost it. The value of the BB based one is, I'm not likely to lose my BB. So we will see how this goes.

I'm still working on a plan. Which things to change, when. For the short term, I will continue to monitor my default behavior, tracking various activities that might impact mood and health. I'm hoping to add pain tracking today, because I have been in a lot of pain the past few days. I may start going to TOPS again, that's difficult with my schedule.

So here we . . .an adventure not so new but hopefully more successful!